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Amitriptyline-fluoxetine

193 bytes removed, 13:53, 2 November 2015
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* '''Before day 0:''' gradually reduce dosage of amitriptyline to a maximum of 25-50 mg/day.* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.* '''Day 3:''' reduce dosage of amitriptyline to 10 mg/day.{{stopAmitriptyline}}
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* '''Day 19:''' simultaneously start administration of fluoxetine in a normal dosage of 20 mg/day.* '''Day 816:''' stop administration of amitriptyline and continue administration if necessary, increase dosage of fluoxetine.
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* Occurrence {{theorSS}}* Fluoxetine and norfluoxetine are inhibitors of serotonin syndrome is theoretically possibleCYP2D6 (strong) and CYP3A4 (moderate), so caution is necessarywhich metabolize amitriptyline.}}
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