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Amitriptyline-fluvoxamine

219 bytes removed, 13:54, 2 November 2015
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* '''Before day 0:''' gradually reduce dosage of amitriptyline to a maximum of 50 mg/day.* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.* '''Day 3:''' reduce dosage of amitriptyline to 10 mg/day.{{stopAmitriptyline}}
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* '''Day 19:''' simultaneously start administration of fluvoxamine in a normal dosage of 50 mg/day.* '''Day 816:''' stop administration of amitriptyline and continue administration increase dosage of fluvoxamine.
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* Occurrence {{theorSS}}* Fluvoxamine is an inhibitor of serotonin syndrome is theoretically possibleCYP1A2, CYP2C19 and CYP3A4 (moderate), so caution is necessarywhich metabolize amitriptyline.}}
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