| to = vortioxetine
| stop =
* '''Before day 1:''' gradually reduce dosage of amitriptyline to a maximum of 50 mg/day.* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.* '''Day 8:''' stop administration of amitriptyline.{{TCAdecrease25p3d}}| start = * '''Day 8:''' start administration of vortioxetine in a normal dosage of 10 mg/day.{{StartAntidepressant}}| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.Safe target dose vortioxetine = 10 mg
}}
