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| to = amitriptyline
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* '''Day 1-3:''' start administration of Start amitriptyline in with a low dosage of 25 mg/day.* '''Day 48:''' increase dosage of amitriptyline to a dosage of 50 mg/day and continue slowly increasing the dosage depending on the condition of the patient.
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* Bupropion slows the metabolism of amitriptyline by via CYP2D6.* Caution is necessary at the start of administration of amitriptyline. {{RiskSeizureBupropionTCA}}* {{TCAplasmalevelmonitoring}}}}
