{{Inc25p3d2}}* '''Day 1:''' Start amitriptyline with a dosage of 25 mg/day.* Start administration '''Day 8:''' increase dosage of amitriptyline in to a low dosage of 25 50 mg/day.
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* Bupropion slows the metabolism of amitriptyline via CYP2D6.
* Caution is necessary at the start of administration of amitriptyline.
