| to = clomipramine
| stop =
* '''Before day 1:''' Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.* '''Day 1:''' Stop administration of bupropion{{stopBupropion}}| start = * '''Day 1-3:''' start administration of clomipramine the next day in a low dosage of 25-50 mg37,5mg/day.* '''Day 48:''' increase dosage of clomipramine to a dosage of 75 mg/day and continue slowly increasing the dosage depending on the condition of the patient.
| info =
* Bupropion slows the metabolism of clomipramine via CYP2D6.
* Caution is necessary at the start of administration of clomipramine.
* {{RiskSeizureBupropionTCA}}
* {{TCAplasmalevelmonitoring}}
}}
