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Bupropion-doxepine

208 bytes removed, 12:32, 4 August 2023
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{{Drugswitch
| from = bupropion
| to = doxepin doxepine
| stop =
* '''Before day 1:''' Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.* '''Day 1:''' Stop administration of bupropion{{StopBupropion}}
| start =
* '''Day 1-3:''' start administration of doxepin the next day in a low dosage of 25 mg25mg/day.* '''Day 48:''' increase dosage of doxepin to 50 a dosage of 75 mg/day and continue slowly increasing the dosage depending on the condition of the patient
| info =
* Bupropion slows the metabolism of doxepin via CYP2D6.
* Caution is necessary at the start of administration of doxepin. {{RiskSeizureBupropionTCA}}* {{TCAplasmalevelmonitoring}}}}

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