| to = imipramine
| stop =
* Gradually reduce dosage of bupropion to a maximum of 150 mg/ day. * When a dosage of 150 mg/day is reached, stop administration.{{stopBupropion}}| start = * '''Day 1-3:''' start administration of imipramine the next day in a low dosage of 25 mg25mg/day.* '''Day 48:''' increase dosage of imipramine to a dosage of 50 mg/day and continue slowly increasing the dosage depending on the condition of the patient.
| info =
* Bupropion slows the metabolism of imipramine by via CYP2D6.* Caution is necessary at the start of administration of imipramine. {{RiskSeizureBupropionTCA}}* {{TCAplasmalevelmonitoring}}}}
