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Type Antidepressant
Group other
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Type Antidepressant
Group MAO-I
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide

Switch medication from bupropion to moclobemide.[1] [2]

Nietinrijdenbord.png Stop bupropion
  • Day 1: Stop bupropion.
  • bupropion can be stopped abruptly for every dosage.[3]
Eenrichtingbord.png Start moclobemide
  • Day 1-7: wash-out period of one week is necessary.
  • Day 8: start moclobemide with 150 mg/day.
  • Day 12: increase moclobemide to 300 mg/day.
  • Day 15: if necessary, increase moclobemide to 600 mg/day.
Infobord.png More information
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Multidisciplinair document Afbouwen Overige Antidepressiva 2023
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