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* '''Day 1-3:''' reduce dosage of clomipramine to 50 mg/day.
* '''Day 4-7:''' reduce dosage of clomipramine to 25 mg/day.
* '''Day 8:''' stop administration of clomipramine.
| start =
* '''Day 1:''' simultaneously start administration of bupropion in a dosage of 150 mg/day and continue administration of clomipramine according to the scheme above.
* '''Day 8:''' stop administration of clomipramine and continue administration of bupropion only in a dosage of 300 mg/day.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes clomipramine.
}}
