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* '''Day 19-15:''' simultaneously start administration of duloxetine in a normal dosage wash-out period of 60 mg/dayone week is necessary.* '''Day 816:''' stop start administration of clomipramine and continue administration duloxetine in a normal dosage of duloxetine60 mg/day.
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* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.{{theorSS}}* Duloxetine is a an inhibitor of CYP2D6, which metabolizes clomipramine.}}
