| to = duloxetine
| stop =
* '''Before day 0:''' gradually reduce dosage of clomipramine to a maximum of 50 mg/day.* '''Day 1:''' reduce dosage of clomipramine to 25 mg/day.* '''Day 7:''' stop dosage of clomipramine.{{TCAdecrease25p3d}}| start = * '''Day 10:''' start administration of duloxetine in a normal dosage of 60 mg/day.{{StartAntidepressant}}| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* Duloxetine is a inhibitor of CYP2D6, which metabolizes clomipramine.Safe target dose duloxetine = 60 mg
}}
