| to = escitalopram
| stop =
* '''Before day 1:''' gradually reduce dosage of clomipramine to a maximum of 50 mg/day.* '''Day 1:''' reduce dosage of clomipramine to 25 mg/day.* '''Day 3:''' reduce dosage of clomipramine to 10 mg/day.* '''Day 8:''' stop administration of clomipramine. {{TCAdecrease25p3d}}| start = * '''Day 1:''' simultaneously start administration of escitalopram in a normal dosage of 10 mg/day.{{StartAntidepressant}}| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* Escitalopram is a very weak inhibitor of CYP2D6, which metabolizes clomipramine.{{review}}Safe target dose escitalopram = 10 mg }}
