Changes

Jump to: navigation, search

Clomipramine-fluvoxamine

106 bytes removed, 15:59, 11 September 2009
no edit summary
| to = fluvoxamine
| stop =
* '''Before day 1:''' gradually reduce dosage of clomipramine to a maximum of 75 50 mg/day.* '''Day 1:''' reduce dosage of clomipramine to 50 25 mg/day.* '''Day 38:''' reduce stop dosage of clomipramine to 25 mg/day.
| start =
* '''Day 18:''' simultaneously start administration of fluvoxamine in a normal dosage of 50 mg/day.* '''Day 815:''' stop administration of clomipramine and continue administration increase dosage of fluvoxamine in a dosage of 50-100 mg/day.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Fluvoxamine is an inhibitor of CYP1A2, CYP2C19 and CYP3A4 (moderate), which metabolize clomipramine.}}
editor, reviewer
154
edits

Navigation menu