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Combining-Aripiprazole-Carbamazepine

33 bytes removed, 15:06, 4 June 2010
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{{Drugcombi
| base = risperidonearipiprazole
| add = carbamazepine
| info =
* This combination of drugs may have possible synergistic effects. However, the pharmacokinetic drug interactions will influence the plasma levels. Dose adaptation will be recommended for this combination.
| start =
* Coadministration with carbamazepine may decrease the plasma concentrations of risperidone and its pharmacologically active metabolite, 9-hydroxyrisperidonearipiprazole via induction of CYP450 3A4.* Risperidone Aripiprazole should be given at higher dosage to control psychotic symptoms. <ref name="drugscom">{{Drugscominteract|risperidonearipiprazole-with-carbamazepine-497233-0-2019497-0|risperidonearipiprazole|carbamazepine}}</ref>
| cave =
* Pharmacologic response and plasma risperidone aripiprazole levels should be monitored more closely whenever carbamazepine is added to or withdrawn from therapy. <ref name="drugscom" />
}}
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