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* The combination may rarely cause neurotoxicity ''without increased plasma levels''. <ref> {{Pubmed|8740344|Marcoux AW. Carbamazepine-lithium drug interaction. Ann Pharmacother 1996;30:547}}</ref>
* The combination of these two drugs in generally safe and effective, but it should be avoided for patients with comorbid CNS(central nervous system) disease.<ref name="freeman">{{Pubmed|9433333|Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21}}</ref>
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