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| base = gabapentin
| add = lithium
| info = * The advantages of gabapentin include the lack of interactions with other drugs in the cytochrome P450 system and the lack of protein binding. Since there is little risk of drug interactions, use with lithium is likely to be safe. <ref name=”freeman”> {{PubmedGabapentinAdvantage|9433333|Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21lithium}}</ref>
| start =
* Start lithium according to the general dosing advice.
| cave =
* Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. <ref name="drugscom">
{{Drugscominteract|lithium-with-gabapentin-1147-0-1477-0|lithium|gabapentin}}</ref>
}}
