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* Lamotrigine is principally metabolised by UDP-glucuronosyltransferases.
* Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
* Start olanzapine lamotrigine according to the general dosing advice.
| cave =
* Coadministration with olanzapine may slightly decrease the plasma concentrations of lamotrigine. <ref name="drugscom">{{DRUGSCOM|olanzapine}}</ref>
}}
