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| add = topiramate
| info =
* Lamoptrigine is principally metabolised by UDP-glucuronosyltransferasesThis combination of drugs may have possible synergistic effects.* Topiramate induces CYP3A4 and is an inhibitor of CYP2C19However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
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* Topiramate does not cause a significant change in lamotrigine levels. Start topiramate according to the general dosing advice. <ref> {{Pubmed|12180999|Berry at al, Lack of an effect of topiramate on lamotrigine serum concentrations. Epilepsia 2002;43(8):818-23}}</ref>Start topiramate according to the general dosing advice.
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