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Combining-Olanzapine-Lithium

159 bytes removed, 09:25, 22 April 2010
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| add = lithium
| info =
* Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
| cave =
* The concomitant administration of lithium with neuroleptic agents may increase the risk of extrapyramidal reactions and neurotoxicity. <ref name="drugscom">
{{Drugscominteract|olanzapine-with-lithium-1477-0-1744-1113|olanzapine|lithium}}</ref>
}}
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