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Combining-Olanzapine-Topiramate

122 bytes removed, 09:26, 22 April 2010
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* Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
* Topiramate induces CYP3A4 and is an inhibitor of CYP2C19.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
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Ashni
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