| info =
* Risperidone is principally metabolized by CYP2D6 to an active metabolite.
* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects<ref name="freeman">{{Pubmed|9433333|Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Dose adaptation will be recommended for this combinationAm J Psychiatry 1998;155:12-21}}</ref>.
| start =
* Start lithium according to the general dosing advice.
