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Dosulepine-agomelatine

647 bytes removed, 12:07, 4 August 2023
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| to = agomelatine
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* '''Before day 0:''' gradually reduce dosage of dosulepine to a maximum of 75 mg/day, when this dosage is > 75 mg/day. * '''Day 1:''' reduce dosage of dosulepine to 50 mg/day.* '''Day 8:''' reduce dosage of dosulepine to 25 mg/day.* '''Day 15:''' stop administration of dosulepine.{{TCAdecrease25p3d}}| start = * '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.* '''Day 15:''' continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day. <ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102StartAgomelatine}}</ref>
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