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Dosulepine-sertraline

488 bytes removed, 12:13, 30 June 2023
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| to = sertraline
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* '''Before day 0:''' gradually reduce dosage of dosulepine to a maximum of 75 mg/day.{{TCAdecrease25p3d}}* '''Day 1:''' reduce dosage of dosulepine to 50 mg/day.* '''Day 3:''' reduce dosage of dosulepine to 25 mg/day.* '''Day 7:''' stop administration of dosulepine.| start = {{StartAntidepressant}}| start info = * '''Day 8:''' start administration of Safe target dose sertraline in a normal dosage of = 50 mg/day.* '''Day 22:''' if necessary increase dosage of sertraline to 100 mg/day.| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* Sertraline is a weak inhibitor of CYP2D6, which metabolizes dosulepine. }}

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