| to = sertraline
| stop =
* '''Before day 1:''' gradually reduce dosage of doxepin to a maximum of 100 mg/day.* '''Day 1:''' reduce dosage of doxepin to 50 mg/day.* '''Day 8:''' reduce dosage of doxepin to 25 mg/day.* '''Day 15:''' stop administration of doxepin.{{TCAdecrease25p3d}}| start = * '''Day 15:''' start administration of sertraline in a normal dosage of 50 mg/day.* '''Day 22:''' if necessary increase sertraline to 100 mg/day.{{StartAntidepressant}}| info = * {{theorSS}}* Sertraline is a weak inhibitor of CYP2D6, which metabolizes doxepin.Safe target dose sertraline = 50 mg{{review}} }}
