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Duloxetine-doxepine

428 bytes removed, 13:51, 30 June 2023
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* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day. * '''Day 1:''' reduce dosage of duloxetine to a maximum of 30 mg/day. {{TCAdecrease25p3d}}
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* '''Day 1:''' simultaneously start administration of doxepin in a low dosage of 25 mg/day.* '''Day 8:''' stop administration of duloxetine and increase the dosage of doxepin to 50 mg/day.{{TCAincrease25p3d}}| info = * Duloxetine slows the metabolism of doxepin by CYP2D6.{{TCAplasmalevelmonitoring}}* Caution is necessary at the start of administration of doxepin. }}

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