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Duloxetine-maprotiline

378 bytes removed, 13:52, 30 June 2023
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| to = maprotiline
| stop =
* '''Before day 1:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/day. * '''Day 1:''' reduce the dosage of duloxetine to 30 mg/day.* '''Day 8:''' stop administration of duloxetine.{{TCAdecrease25p3d}}| start = No wash-out period is needed.* '''Day 8:''' start administration of maprotiline in a low dosage of 25 mg/day.* '''Day 15:''' increase the dosage of maprotiline to 50 mg/day.{{TCAincrease25p3d}}| info = * Duloxetine slows the metabolism of maprotiline by CYP2D6.{{reviewTCAplasmalevelmonitoring}}
}}

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