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Fluoxetine-amitriptyline

130 bytes removed, 14:40, 28 October 2015
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| to = amitriptyline
| stop =
* '''Day 0:''' Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * '''Day 1:''' When a dosage of 20 mg/day is reached, stop administration.{{stopFluoxetine1}}
| start =
Caution is necessary for at least four weeks.
* '''Day 1-8:''' wash-out period. * '''Day 82:''' start administration of amitriptyline in a low dosage of 25 mg/day* . * '''Day 15:''' if necessary, increase dosage of amitriptyline to 50-150 mg/day.* '''Day 29:''' gradually increase dosage of amitriptyline.
| info =
* Fluoxetine slows and norfluoxetine slow the metabolism of amitriptyline via CYP2D6. * Start low, go slow for amitriptyline.* {{theorSS}}  }}
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