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{{Drugswitch
| from = fluoxetine
| to = bupropion
| stop =
| start =
* '''Day 12:''' no start administration of fluoxetine and bupropion (“wash-out” period in a low dosage of one 150 mg/day).* '''Day 230:''' start administration if necessary gradually increase bupropion to 300 mg/day. | info =* Bupropion inhibits CYP2D6 which metabolizes fluoxetine.{{longt1/2fluvox}}* Because of the normal half-life of 1 week of bupropion in desmethylfluoxetine, there should be a low dosage dosing of 150 mg/daybupropion during 4 weeks. }}
