* '''Day 9-372:''' start administration of bupropion in a low dosage of 150 mg/day.* '''Day 37 and on30:''' if necessary gradually increase bupropion to 300 mg/day.
| info =
* Bupropion inhibits CYP2D6 which metabolizes fluoxetine.
{{longt1/2fluvox}}
* Because of the normal half-life of 1 week of desmethylfluoxetine, there should be a low dosing of bupropion during 4 weeks.