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| start =
No wash-out period is needed.
* '''Day 1:''' start mianserine the next day in low dosage of 30 mg/day for one week.
* '''Day 21:''' increase dosage of mianserine to normal, 60 mg/day.
| info =
* (Desmethyl)Fluoxetine has a very long elimination time; phasing out fluoxetine is therefore not necessary.
* Fluoxetine slows the metabolism of minaserine mianserine through CYP2D6.
}}
