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Hypericum-amitriptyline

83 bytes removed, 15:09, 4 August 2023
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| to = amitriptyline
| stop =
* '''Day 1-14:'''Gradually decrease the dosage of hypericum. * '''Day 15:''' stop administration of hypericum.{{Stophyp}}
| start =
* '''Day 15-30:''' a wash-out period of at least two weeks is necessary. {{TCAincrease25p3d}}* '''Day 31:''' start amitriptyline 25 mg/day.| caveat = * Occurrence of the serotonin syndrome is possible without wash-out period.
| info =
{{TCAplasmalevelmonitoring}}
* The ratio of amitriptyline/nortriptyline could change because of CPY2C19 induction. Sum plasmalevels are not likely to change because CYP2D6 is barely affected.
{{caveSS}}
{{HypericumInfo}}
 
}}

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