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Hypericum-tranylcypromine

1,009 bytes removed, 8 March
no edit summary
| to = tranylcypromine
| stop =
* '''Day 1-14:'''Gradually decrease the dosage of hypericum. {{Dec25p3d}}* '''Day 15:''' stop administration of hypericum.{{7dWashout}}
| start =
* '''Day 15-22:''' a wash-out period of at least one week 7 days is necessary..<ref>{{Pubmed|18294328|Imai H, Kotegawa T, Tsutsumi K, Morimoto T, Eshima N, Nakano S, Ohashi K. The recovery time-course of CYP3A after induction by St John's wort administration. Br J Clin Pharmacol. 2008 May;65(5):701-7.Starttranyl}}</ref><ref>{{Pubmed|16640452|Wurglics M, Schubert-Zsilavecz M. Hypericum perforatum: a 'modern' herbal antidepressant: pharmacokinetics of active ingredients. Clin Pharmacokinet. 2006;45(5):449-68.}}</ref><ref>{{Pubmed|19593191|Derijks HJ, Janknegt R, Heerdink ER, De Koning FH, Krekels MM, Looij BJ, Egberts AC. Influence of antidepressant use on glycemic control in patients with diabetes mellitus: an open-label comparative study. J Clin Psychopharmacol. 2009 Aug;29(4):405-8.}}</ref><ref name="informatorium">{{KNMP|tranylcypromine}}</ref> * '''Day 23:''' start tranylcypromine 10 mg/day.* '''Day 38:''' escalate dosage if necessary
| caveat =
* Occurrence of the serotonin syndrome is possible without wash-out period.{{caveSS}}
| info =
{{HypericumInfo}}
{{nointeractions}}
}}

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