Difference between revisions of "Hypericum-trazodone"

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* If necessary, increase dosage of trazodone further.
 
* If necessary, increase dosage of trazodone further.
 
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* Occurence of the serotonin syndrome is theoretically possible. }}
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* Occurrence of the serotonin syndrome is theoretically possible. }}

Revision as of 15:30, 7 May 2009

Hypericum
Type Antidepressant
Group other
links
EMEA 10130408en
PubMed Hypericum
Kompas (Dutch) hypericum extract
Wikipedia St John's wort
Trazodone
Type Antidepressant
Group other
links
Medscape Trazodone
PubChem 5533
PubMed Trazodone
Kompas (Dutch) Trazodone
Wikipedia Trazodone

Switch medication from hypericum to trazodone.[1] [2]

Nietinrijdenbord.png Stop hypericum
  • Administration of hypericum can be stopped abruptly.
Eenrichtingbord.png Start trazodone
  • Day 1-7: a wash-out period of one week is necessary.
  • Day 8: start administration of trazodone in a dosage of 150 mg/day.
  • Day 15: increase dosage of trazodone to 300 mg/day.
  • If necessary, increase dosage of trazodone further.
Infobord.png More information
  • Occurrence of the serotonin syndrome is theoretically possible.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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