Changes

Jump to: navigation, search

Imipramine-sertraline

267 bytes removed, 14:38, 4 November 2015
no edit summary
| to = sertraline
| stop =
* '''Before day 1:''' gradually reduce dosage of imipramine to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of imipramine to 50 mg/day.* '''Day 3:''' reduce dosage of imipramine to 25 mg/day.{{stopImipramine}}
| start =
* '''Day 4:''' simultaneously start administration of sertraline in a normal dosage of 50 mg/day.
* '''Day 8:''' stop administration of imipramine and continue administration of sertraline in a dosage of 50-100 mg/day.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.{{theorSS}}
* Sertraline is a weak inhibitor of CYP2D6, which metabolizes imipramine.
{{review}}
}}
editor
1,352
edits

Navigation menu