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Imipramine-trazodone

370 bytes removed, 14:46, 4 November 2015
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| to = trazodone
| stop =
* '''Before day 0:''' gradually reduce dosage of imipramine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. * '''Day 1:''' reduce dosage of imipramine to 25 mg/day.* '''Day 8:''' stop administration of imipramine.{{stopImipramine}}
| start =
No wash-out period is needed.
* '''Day 4:''' simultaneously start administration of trazodone in a dosage of 150 mg/day.
* '''Day 8:''' continue only administration of trazodone. * {{upTrazo}}If necessary, increase the dosage of trazodone to a maximum of 400 mg/day.
| info =
* Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.{{theorSS}}}}
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