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Maprotiline-citalopram

349 bytes removed, 12:37, 30 June 2023
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| to = citalopram
| stop =
* '''Before day 1:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of maprotiline to 50 mg/day.* '''Day 7:''' reduce dosage of maprotiline to 25 mg/day.* '''Day 14:''' stop administration of maprotiline.{{TCAdecrease25p3d}}| start = * '''Day 7:''' simultaneously start administration of citalopram in a normal dosage of 20 mg/day.{{StartAntidepressant}}| info = * Citalopram is a weak inhibitor of CYP2D6, which metabolizes maprotiline. Safe target dose citalopram = 20 mg
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