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Maprotiline-escitalopram

352 bytes removed, 12:46, 30 June 2023
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| to = escitalopram
| stop =
* '''Before day 1:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of maprotiline to 50 mg/day.* '''Day 7:''' reduce dosage of maprotiline to 25 mg/day.* '''Day 14:''' stop administration of maprotiline.{{TCAdecrease25p3d}}| start = * '''Day 7:''' simultaneously start administration of escitalopram in a normal dosage of 10 mg/day.{{StartAntidepressant}}| info = * Escitalopram is a weak inhibitor of CYP2D6, which metabolizes maprotiline. Safe target dose escitalopram = 10 mg
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