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Mirtazapine-fluvoxamine

360 bytes removed, 10:11, 29 October 2021
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| to = fluvoxamine
| stop =
* '''Day 0:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.{{stopMirtazapine}}* '''Day 1:''' reduce a dosage of 30 mg/day to 15 mg/day.| start = * '''Day 8:''' stop administration of mirtazapineNo wash-out period is needed.| start = * '''Day 119:''' start fluvoxamine in a normal dosage of 50 mg/day.* '''Day 14:''' If necessary, increase dosage of fluvoxamine to 100 mg/day. | info = * Caution with this switch is necessary, because fluvoxamine slows the metabolism of mirtazapine via CYP1A2, CYP2C9, CYP2D6 and CYP3A4.}}

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