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Mirtazapine-fluvoxamine

367 bytes removed, 10:11, 29 October 2021
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| to = fluvoxamine
| stop =
* '''Day 0:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.* '''Day 1:''' reduce a dosage of 30 mg/day to 15 mg/day.{{stopMirtazapine}}| start = * '''Day 1:''' simultaneously start fluvoxamine in a normal dosage of 50 mg/dayNo wash-out period is needed.* '''Day 89:''' stop administration of mirtazapine and only continue administration of start fluvoxamine in a normal dosage of 50-100 mg/day. | info = * Caution with this switch is necessary, because fluvoxamine slows the metabolism of mirtazapine via CYP1A2, CYP3A4 and CYP2D6.}}

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