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Nortriptyline-bupropion

132 bytes removed, 17:25, 28 October 2015
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| to = bupropion
| stop =
* '''Before day 1:''' gradually reduce dosage of nortriptyline to a maximum of 50 mg/day, when this dosage is > 50 mg/day.* '''Day 1-3:''' reduce dosage of nortriptyline to 25 mg/day.{{stopNortriptyline}}
| start =
* '''Day 1:''' simultaneously start administration of bupropion in a dosage of 150 mg/day and continue administration of nortriptyline according to the scheme above.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes nortriptyline.
* Caution with this switch is necessary. * {{RiskSeizureBupropionTCA}}}}
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