| to = paroxetine
| stop =
* '''Before day 1:''' gradually reduce dosage of nortriptyline to a maximum of 50 mg/day.* '''Day 1:''' reduce dosage of nortriptyline to 25 mg/day.* '''Day 3:''' reduce dosage of nortriptyline to 10 mg/day.{{downNortriptyline}}| start = * '''Day 1:''' simultaneously start administration of paroxetine in a low dosage of 10 mg/day.* '''Day 8:''' stop administration of nortriptyline and continue administration of paroxetine in a dosage of 20 mg/day.{{startmapnorcyp2d6}}
| info =
* Paroxetine is a strong inhibitor of [[wp:CYP2D6|CYP2D6]], which metabolizes nortriptyline. * Safe target dose paroxetine = 20 mg
}}
