[[File{{Drugswitch | from = paroxetine| to = vortioxetine | stop = {{downparox}}| start = * '''Day 15-18:Empty''' a wash-out period of 3 days is to prevent inhibition of the metabolism of vortioxetine.jpg]]* '''Day 18:''' start administration of vortioxetine in a normal dosage of 10 mg/day.| info = * Paroxetine is a strong inhibitor of CYP2D6, which metabolizes vortioxetine. * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary. }}