| to = amitriptyline
| stop =
* '''Day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/day when this dosage is > 50 mg/day. * '''Day 1:''' reduce dosage of sertraline to a maximum of 25 mg/day.* '''Day 8:''' stop administration of sertraline. {{TCAdecrease25p3d}}
| start =
Caution is necessary.* '''Day 1:''' simultaneously start administration of amitriptyline in a low dosage of 25 mg/day. * '''Day 8:''' continue administration of amitriptyline in a dosage of 50 mg/day.* Start low, go slow!{{TCAincrease25p3d}}| info = * Sertraline dose-dependently slows the metabolism of amitriptyline via CYP2D6. * {{theorSSTCAplasmalevelmonitoring}}
}}
