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  • In general after long-term maintenance treatment, the best is to reduce the dose by about 25% every 4-6 weeks. An apt pharmaceutical dose (tablet, capsule, mixture) is not always available. In these cases one should be creative with dosing. [1] [2]
  • An other possibility is being at a certain dose to use the following scheme:
  • The UK Drug and Therapeutics Bulletin; 1999;37:49-52
  • Editor: please note that not all dosages are available in pharmacy. So now and then you should be creative.