Difference between revisions of "Template:Switch-to-(9OH-)risperidone"

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There are 2 switch possibities:
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''There are 2 switch possibities'':
  
'''The general Number 1'''  
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'''Number 1 (the general approach):'''  
* Day 1: Switch to oral risperidone (or oral paliperidone): see this switch in the main cross table.
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* '''Day 1:''' Switch to oral risperidone (or oral paliperidone): see this switch in the main cross table.
* Day 1-29: Maintain on oral risperidone (or oral paliperidone) and examine the effects.
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* '''Day 1-29:''' Maintain on oral risperidone (or oral paliperidone) and examine the effects.
* Day 30: stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table.
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* '''Day 30:''' stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table.
  
'''If a patient in the past reacted well on risperidon or paliperidone(=9-OH-risperidone) Number 2'''
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Oral risperidone has better and more stable bioavailability properties than has oral 9-OH-risperidone=paliperidone. Food increases the absorption with 50-60% of the latter.
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'''Number 2 (if a patient in the past reacted well on risperidon or paliperidone=9-OH-risperidone):'''

Latest revision as of 16:57, 16 May 2011

There are 2 switch possibities:

Number 1 (the general approach):

  • Day 1: Switch to oral risperidone (or oral paliperidone): see this switch in the main cross table.
  • Day 1-29: Maintain on oral risperidone (or oral paliperidone) and examine the effects.
  • Day 30: stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table.

Oral risperidone has better and more stable bioavailability properties than has oral 9-OH-risperidone=paliperidone. Food increases the absorption with 50-60% of the latter.


Number 2 (if a patient in the past reacted well on risperidon or paliperidone=9-OH-risperidone):