| to = hypericum
| stop =
* Gradually decrease the dosage of tranylcypromine with 10-20 mg/week. * When a dosage of 10 mg/day is reached, stop administration.{{stopTranyl}}
| start =
* {{Inc25p3do50pw}}<ref>{{Pubmed|18294328|Imai H, Kotegawa T, Tsutsumi K, Morimoto T, Eshima N, Nakano S, Ohashi K. The recovery time-course of CYP3A after induction by St John'''Day 1s wort administration. Br J Clin Pharmacol. 2008 May;65(5):701-7.}}</ref><ref>{{Pubmed|16640452|Wurglics M, Schubert-14Zsilavecz M. Hypericum perforatum:''' a wash-out period of two weeks is necessary. * 'modern''Day 15herbal antidepressant:''' start hypericum after this period in a dosage pharmacokinetics of 300 mg three times a day active ingredients. Clin Pharmacokinet. 2006;45(900 mg/day5):449-68.}}</ref><ref name="informatorium">{{KNMP|tranylcypromine}}</ref>
| info =
* Occurence of the serotonin syndrome is theoretically possible.{{Tcrestore}} * The wash-out period is necessary for the MAO enzymes to restore their function.}}
