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* '''Day 1-14:''' a wash-out period of two weeks is necessary.
* '''Day 15:''' start administration of vortioxetine in a normal dosage of 10 mg/day.
| caveat =
* Occurrence of the serotonin syndrome is possible without a wash-out period.
| info =
* The wash-out period is necessary for the MAO enzymes to restore their function.
}}
