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Trazodone-bupropion

206 bytes removed, 12:36, 4 November 2015
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| to = bupropion
| stop =
* '''Before day 0:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day. * '''Day 1:''' reduce dosage of trazodone to 75 mg/day.* '''Day 8:''' stop administration of trazodone.{{stopTrazodone}}
| start =
* A wash-out period is not necessary, but care is needed.
* '''Day 8:''' simultaneously start administration of bupropion in a normal dosage of 150 mg/day.
* '''Day 15:''' increase dosage of bupropion to 300 mg/day.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes trazodone.{{trazoTablet}} }}
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