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Trazodone-citalopram

579 bytes removed, 17:38, 24 February 2023
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| from = trazodone
| to = citalopram
| stop = * '''Before day 0:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day{{StopSSRI, when this dosage is > 150 mg/day. * '''Day 1:''' reduce dosage of trazodone to 75 mg/day.* '''Day 8:''' stop administration of trazodone.SNRI}}| start = {{StartAntidepressant}}* A wash-out period is not necessary.| info =* '''Day 1:''' simultaneously start administration of Safe target dose citalopram/escitalopram in a normal dosage of = 20 mg/day, resp. 10 mg/day.* '''Day 8:''' stop administration of trazodone and continue administration of citalopram/escitalopram.{{theorSS}}| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* Citalopram/escitalopram are a weak inhibitor of CYP2D6, which metabolizes trazodone.}}

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